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The proposed course is framed for UG students in the life science or biological sciences domain. Through this course, the students will be able to address some questions like, How do we find potentially harmful mutations in your genome? How can we reconstruct the evolutionary Tree of Life? How do we compare related genes from different species? These are just three of the major questions in modern biology that can only be answered using bioinformatics approaches. The course will delve into computational ideas used in biology as well as let students apply existing resources that are used in practice every day by bioinformatics professionals. The course offers an opportunity for students who possess a biological background to become more familiar with the biological process occurring within an organism at genetic level.
Overview
Syllabus
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COURSE LAYOUT
Weeks Weekly Lecture TopicsWeek 1 Day 1 Module 1: Origin, History, and Scope of BioinformaticsDay 2 Module 2: Importance and Use of BioinformaticsDay 3 Module 3: Applications of BioinformaticsDay 4 Interaction based on the three modules coveredDay 5 Deadline for submitting assignments
Week 2 Day 1 Module 4: IT in teaching, Learning and ResearchDay 2 Module 5: Open Access Bibliographic ResourcesDay 3 Module 6: Basic Concepts of Copyrights and PatentsDay 4 Interaction based on the three modules coveredDay 5 Deadline for submitting assignments
Week 3 Day 1 Module 7: Central Dogma and Emergence of Omics TechnologiesDay 2 Module 8: Genomics and TranscriptomicsDay 3 Module 9: Proteomics and MetabolomicsDay 4 Interaction based on the three modules coveredDay 5 Deadline for submitting assignments
Week 4 Day 1 Module 10: Introduction to Biological DatabasesDay 2 Module 11: Sequence and Structural DatabasesDay 3 Module 12: Functional and Other DatabasesDay 4 Interaction based on the three modules coveredDay 5 Deadline for submitting assignments
Week 5 Day 1 Module 13: Basic Concepts of Sequence Similarity and IdentityDay 2 Module 14: File Formats for SequencesDay 3 Module 15: Sequence – Patterns and ProfilesDay 4 Interaction based on the three modules coveredDay 5 Deadline for submitting assignments
Week 6 Day 1 Module 16: Scoring MatricesDay 2 Module 17: Sequence – Pairwise alignmentsDay 3 Module 18: Multiple Sequence AlignmentsDay 4 Interaction based on the three modules coveredDay 5 Deadline for submitting assignments
Week 7 Day 1 Module 19: GenBankDay 2 Module 20: BLASTDay 3 Module 21: Protein Data Bank (PDB)Day 4 Interaction based on the three modules coveredDay 5 Deadline for submitting assignments
Week 8 Day 1 Module 22: Taxonomy and PhylogenyDay 2 Module 23: Phylogenetics – MethodsDay 3 Module 24: Phylogenetics – ToolsDay 4 Interaction based on the three modules coveredDay 5 Deadline for submitting assignments
Week 9 Day 1 Module 25: Molecular ModellingDay 2 Module 26: Molecular visualization – Rasmol and PymolDay 3 Module 27: Molecular dockingDay 4 Interaction based on the three modules coveredDay 5 Deadline for submitting assignments
Week 10 Day 1 Module 28: Definition of Drugs and its AdvancesDay 2 Module 29: Pharmacophore Identification and Novel Drug DesignDay 3 Module 30: Structure based drug designDay 4 Interaction based on the three modules coveredDay 5 Deadline for submitting assignments
Week 11 Day 1 Module 31: DNA sequencing – Basic methodsDay 2 Module 32: Next Generation Sequencing (NGS)Day 3 Module 33: Human Genome ProjectDay 4 Interaction based on the three modules coveredDay 5 Deadline for submitting assignments
Week 12 Day 1 Module 34: Protein structure – PrimaryDay 2 Module 35: Protein structure - SecondaryDay 3 Module 36: Protein structure - Tertiary and QuaternaryDay 4 Interaction based on the three modules coveredDay 5 Deadline for submitting assignments
Week 13 Day 1 Module 37: Protein Structure PredictionDay 2 Module 38: Protein Interaction analysis
Day 3 Module 39: Gene Predication
Day 4 Interaction based on the three modules coveredDay 5 Deadline for submitting assignments
Week 14
Day 1 Module 40: Mapping Populations
Day 2 Interaction based on the module covered
Day 3 RevisionDay 4 End term assessme
