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This course surveys the reactions of organic compounds with an emphasis on mechanisms and a structure-based approach to understanding reactivity. Concepts and models are developed to build intuition about the reactivity of organic compounds. These concepts will prepare students for a mechanistic-based approach to learning organic reactivity. Emphasis will also be placed on developing problem-solving skills unique to organic chemistry. This course, orgchem1b, together with its prerequisite, orgchem1a are equivalent to a first-semester organic chemistry course; these courses and the subsequent courses (orgchem2a and orgchem2b) are especially suited for students in agricultural, nutritional and biological sciences, as well as premedical, predental, and preveterinary programs.
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Lesson
Topic
1
Subst & Elimination Stereochem
2
Carbocation RAR
3
LGs & Ring-Opening
4
Carbon Nucleophiles
5
E+ Addition to C=C
6
E+ Addition to C≡C
7
Stereochem of E+ Addn
8
Carbonyl Reactivity
9
C=O & Conjugate Addn
10
Acyl Substitution
11
Substitution + Addition
12
Substitution of =O
13
Enols and Enolates
14
The C-alpha nucleophile
15
Exam Review
16
Aldol Addition
17
Claisen Condensation
18
Aromatic Chemistry
19
Aromatic Subst (E+)
20
Aromatic Subst (other)